Liposome – A Trending Novel Drug Delivery System
In recent years, liposomes have garnered significant interest of researchers, as well as industry players, owing to their potential in diagnosis and treatment of various diseases, with a focus on delivering drugs and genetic material.
Liposomes are small, artificial and lipid-based bilayered spherical vesicles, which are created spontaneously by hydrated phospholipids. Owing to their ability to encapsulate bioactive hydrophilic, amphipathic, and lipophilic molecules, liposomes are extensively used as efficient delivery systems for antigens or drugs. They can protect a drug from being detected by the body’s immune system by imitating biological membranes and providing the drug more time to reach its target destination.
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Liposomes offer great therapeutic efficacy and safety. They have several applications in the biomedical field such as delivering drug to the desired site while minimizing drug exposure to normal tissues, increased delivery of potential medications to the cytosol, stabilizing therapeutic compounds, and removing barriers to cellular and tissue absorption.
In addition to the applications, liposomes are gaining popularity across various other fields, including drug delivery, agriculture, cosmetics, and food industry. Due to multiple advantages across diverse application areas, including enhanced biocompatibility, high biodegradability, low toxicity, weak immunogenicity, increased drug solubility, controlled distribution, ability to make surface modifications for targeted, extended, and sustained release, liposomes have been recognized as the most effective delivery system. Currently, there are several liposomal formulations clinically approved for the treatment of various diseases, including cancer, fungal and viral infections, and many are currently in advanced stages of clinical studies. Over the years, several companies involved in the development of liposomes have made significant efforts in conducting clinical trials for evaluating the efficacy of liposome-based therapeutics, for the treatment of various oncological disorders.
Owing to various advantages offered by liposomes, advanced liposome technology is being developed to fully substructure the therapeutic applications of liposomes and extensive research is being conducted to develop methods for liposomal formulation with high level of purity and sensitivity. Further, it is extremely desirable to develop novel manufacturing methods that allow for simple encapsulation of both hydrophobic and hydrophilic molecules without the need of organic solvents, specialized equipment, or complex infrastructures. Additionally, given that liposomes have demonstrated some clinical promise as drug delivery systems, future efforts should focus on enhancing the commercial availability and accessibility of liposome products across the globe, particularly in low- and middle-income countries. applications of liposomes in drug delivery (24%), and protein and peptide delivery (9%), which is indicative of the extensive research activities and clinical trials being conducted to evaluate the therapeutic potential of liposomes.
Despite several advancements, there are various challenges in development of liposomes, for which stakeholders are leveraging the expertise of various contract service providers offering development and manufacturing services. These service providers are actively upgrading their capabilities and infrastructure to accommodate the demand for these vesicles. Driven by the growing research efforts, development of advanced methods for preparation and characterization of liposomes, and efforts of various stakeholders, this segment of industry is likely to witness noteworthy growth in the foreseen future.
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About Roots Analysis
Roots Analysis is a global leader in the pharma / biotech market research. Having worked with over 750 clients worldwide, including Fortune 500 companies, start-ups, academia, venture capitalists and strategic investors for more than a decade, we offer a highly analytical / data-driven perspective to a network of over 450,000 senior industry stakeholders looking for credible market insights.
Contact:
Ben Johnson
+1 (415) 800 3415
Ben.johnson@rootsanalysis.com
Satta King 786 | Selects the Correct Number
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Viral clearance and viral testing services market
Roots Analysis have analyzed patents based on various relevant parameters, such as type of patent, patent publication year, annual number of patent applications, type of applicant, emerging focus areas, and geographical location.
Further, we have also highlighted the Cooperative Patent Classification (CPC) symbols and leading players (in terms of number of patents filed / granted). Moreover, the module includes an informed patent benchmarking analysis of the top patent applicants, along with an analysis of the relative valuation of patents filed / granted related to viral clearance testing, based on several parameters, such as patent age, region in which patent is filed / granted and number of citations.
For the purpose of this analysis, information on patents was extracted from a reliable database, lens.org. The database groups patent applications into different patent families and covers intellectual property documents filed with different patent offices, across the globe. Around 65% of the patents filed related to viral clearance and viral testing were applications (not having received approval yet), followed by granted patents. It is worth highlighting that, the maximum number of patents (over 5 related to this domain were filed / granted in 2020. Further, close to 35 patents have been filed / granted in 2022 (till September)
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Based on several relevant parameters, such as patent type, patent age, number of citations, and region, the patents were allotted different valuation scores. Our analysis indicates that only 1% of patents have the highest relative valuation, based on the parameters and the cut-off of the weighted score considered for this analysis. This is primarily because of the relatively low citations of the patents that have been filed recently, leading to low patent value.
In terms of Geography, most of the patents (36%) were filed / granted in Asia-Pacific. Within this region, the maximum number of patents (over 4 were filed in China. This is followed by North America, where 32% of the total patents were filed / granted. The number of patents is indicative of the extensive research activity taking place in these regions. more than 85% of the players efficiently analyze antibodies for viral contamination, followed by players that have capability to analyze cell and gene therapies, vaccines and recombinant proteins (59%, each) for viral contamination
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About Roots Analysis
Roots Analysis is a global leader in the pharma / biotech market research. Having worked with over 750 clients worldwide, including Fortune 500 companies, start-ups, academia, venture capitalists and strategic investors for more than a decade, we offer a highly analytical / data-driven perspective to a network of over 450,000 senior industry stakeholders looking for credible market insights.
Contact:
Ben Johnson
+1 (415) 800 3415
Ben.johnson@rootsanalysis.com
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The AI-based digital pathology market is projected to grow at an annualized rate of 8.3%, claims Roots Analysis
Driven by continuous innovation within pathology subdomains to improve care delivery paradigms across clinical practices, and active R&D efforts undertaken by industry stakeholders, the AI based digital pathology market is likely to witness significant growth in the coming years
Roots Analysis has announced the addition of “AI-based Digital Pathology Market, 2022-2035” report to its list of offerings.
The use of technical advancements to automate and digitize medical operations is expanding, in conjugation with the continuously growing need for pathology services. These innovations have recently expedited clinical diagnosis and research, as well as improved patient outcomes. Given the rise in popularity and demand for such services in the healthcare and research sectors, as well as the ongoing efforts of AI in pathology providers to enhance their respective portfolios, this market is expected to grow at a steady pace, till 2035.
Key Market Insights
Presently, close to 80 players are actively providing AI-based digital pathology services
More than 45% of the players are located in North America. Within North America, 85% of the AI-based digital pathology providers are based in the US. Further, the domain primarily features the presence of small companies (less than 50 employees), which constitute over 45% of the overall share.
More than 60% of companies provide whole slide imaging and laboratory information systems
Majority (70%) of the players are providing whole slide imaging for research applications. Additionally, over 20% of such players are offering the aforementioned service for diagnostic applications. Further, 72% of the players are providing laboratory information systems for research purposes.
~75% AI-based digital pathology providers are offering their services to research institutes
Close to 60 companies are offering services to research institutes. Further, 48 companies are providing its services to laboratories / diagnostic institutions. It is worth highlighting that close to 30 AI-based digital pathology providers are offering their services to hospitals / healthcare institutions.
Over 35% players are offering AI-based digital pathology services for detection of breast cancer
More than 50% of players are offering Ki67 assay. Among other target disease indications, Ki67 is primarily used to detect breast cancer. Further, close to 25% of players are offering AI-based digital pathology services to detect prostate cancer.
USD 1.7+ billion has been invested across different funding rounds, between 2016 and 2022
Companies involved in offering AI-based digital pathology services have raised more than USD 900 million through venture capital rounds, which represents 55% of the total capital raised in this market between 2016 to 2022. Further, close to 15% of investments have been raised via seed rounds.
Global demand for AI-based digital pathology is expected to grow at a CAGR of 9.4%, during 2022-2035
In 2035, more than 45% of the overall demand for AI-based digital pathology services is anticipated to be driven by research institutes. Furthermore, it is projected that North America (43%) will drive a majority share of the global demand for AI-based digital pathology services.
The market in Middle East and North Africa is anticipated to grow at a faster pace (14.1%), till 2035
Considering the anticipated notable increase in demand for AI-based digital pathology services, over the coming years, this billion-dollar market is expected to be well distributed across key segments. Services focused on research applications are expected to capture close to 50% of the market share by 2035.
To request a sample copy / brochure of this report, please visit this https://www.rootsanalysis.com/....reports/ai-based-dig
Key Questions Answered
Who are the leading players engaged in offering AI-based digital pathology in the healthcare domain?
Which geographies emerged as key hubs for AI-based digital pathology providers?
Which types of end-users are primarily employing AI in digital pathology in their regular workflow?
What type of funding initiatives are most commonly being reported by stakeholders in this domain?
What are the key strategies that can be implemented by emerging players to enter the AI-based digital pathology market?
What are the key market trends and driving factors that are likely to impact the growth of the AI-based digital pathology market?
How is the current and future opportunity likely to be distributed across key market segment?
The financial opportunity within the AI-based digital pathology market has been analyzed across the following segments:
Type of Neural Network
Artificial Neural Network
Convolutional Neural Network
Fully Convolutional Network
Recurrent Neural Network
Other Neural Networks
Type of Assay
ER Assay
HER2 Assay
Ki67 Assay
PD-L1 Assay
PR Assay
Other Assays
End-user
Academic Institutions
Hospitals / Healthcare Institutions
Laboratories / Diagnostic Institutions
Research Institutes
Other End-users
Area of Application
Diagnostics
Research
Other Areas of Application
Target Disease Indication
Breast Cancer
Colorectal Cancer
Cervical Cancer
Gastrointestinal Cancer
Lung Cancer
Prostate Cancer
Other Indications
Key Geographies
North America
Europe
Asia
Latin America
Middle East and North Africa
Rest of the World
Key Countries
US
Canada
UK
Germany
Spain
Italy
France
China
Japan
South Korea
Brazil
Saudi Arabia
Australia
The report features inputs from eminent industry stakeholders, according to whom, AI-based digital pathology is increasingly being recognized in the healthcare industry. The report includes detailed transcripts of discussions held with the following experts:
Joe Yeh (Chief Executive Officer and Chairman, aetherAI)
Suraj Bramhane (Laboratory Director and Chief Pathologist, Clinitech Laboratory)
Savvas Damaskinos (Vice President, Research and Technology, Huron Digital Pathology)
Anil Berger (Vice President, Sales and Marketing, Mindpeak)
Scott Wallace (Vice President, Business Development and Strategic Partnerships, Pramana)
The report includes brief profiles of key players (listed below); each profile features an overview of the company and recent developments related to its AI-based digital pathology offerings:
PathAI
Paige
Akoya Biosciences
PROSCIA
Visiopharm
Roche Tissue Diagnostics
Aiforia Technologies
Indica Labs
Ibex Medical Analytics
For additional details, please visit https://www.rootsanalysis.com/....reports/ai-based-dig or email sales@rootsanalysis.com
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1. Smart Labels Market: Industry Trends and Global Forecasts, 2022-2035
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About Roots Analysis
Roots Analysis is a global leader in the pharma / biotech market research. Having worked with over 750 clients worldwide, including Fortune 500 companies, start-ups, academia, venture capitalists and strategic investors for more than a decade, we offer a highly analytical / data-driven perspective to a network of over 450,000 senior industry stakeholders looking for credible market insights.
Contact:
Ben Johnson
+1 (415) 800 3415
Ben.johnson@rootsanalysis.com